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Infect is a keyword ability.
What is infect?Creatures with infect deal damage to players and creatures in different ways than other creatures.
This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.
You've probably heard of +1/+1 counters. Creatures like Feral Hydra can put +1/+1 counters on themselves. An creature with Infect deals damage to creatures in -1/-1 counters instead of just dealing normal damage. Suppose an 2/2 Creature with Infect like Contagious Nim attacks. If the other player blocks with a 3/3, then instead of nothing happening when Contagious Nim deals its damage, it puts two -1/-1 counters on the 3/3 creature instead of dealing 2 damage. Now, the 3/3 creature is only a 1/1 creature. From then on, the creature weaker permanently unless they get +1/+1 counters again, negating its effects. Another part of Infect is that it deals poison counters to players. Normally, if a 2/2 creature attacks, and the opposing player lets the damage go through, that player would simply lose 2 life. But with infect, the player would get 2 poison counters instead. Here's the important thing: a player with 10 or more Poison counters loses the game.
There's only one way to get rid of poison counters: Leeches.